O-Rings are torus-shaped (i.e. doughnut-shaped) objects made from elastomeric compounds such as natural or synthetic rubber, and are used to seal mechanical parts against fluid movement (air or liquid). O-Rings perform their sealing action by deforming to take the shape of their cavity, after being oversized to guarantee an predetermined interference fit.
O-Rings are inserted into cavities defined as glands, and are typically used in one of two seal designs, axial or radial. These seal designs along with their gland geometries are shown in the following schematic:

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In order for an O-Ring to seal against the movement of fluid, it must be compressed when seated inside the gland. A standard set of design guidelines exist to determine the proper O-Ring dimensions for radial and axial seals of a given dimension.